Measuring the heart’s blood flow behaviour in 3D

An artificial ventricle – imaged alone on the ultrasound scanner – was made with a circulation system to simulate blood flowing in a heart chamber.

Given that cardiovascular related diseases are the most probable cause of death globally, according to WHO, we believe that more information regarding blood behaviour can help the doctors make better diagnosis at an earlier stage. But how can you measure these properties inside the heart, behind the ribs, under the skin, without moving the patients from their bed?

By Morten Smedsrud Wigen, PhD Candidate, Department of Circulation and Medical Imaging and CIUS – Centre for Innovative Ultrasound Solutions.

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Ultrasound – a cross-sector solution

Collage of speakers at CIUS Spring Conference 2017.

Cracks, unevenness, leakages, or speed and direction of liquid flows in vessels or pipes, hearts or pumps, are challenges faced by people in healthcare, oil & gas and the maritime sector. At the Centre for Innovative Ultrasound Solutions (CIUS), we work on improving ultrasound technology and usage to address these…

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Microbubbles and focused ultrasound cure tumours in mice

Illustration: Ultrasound applied to tumors after injecting clusters of microbubbles/microdroplets causes giant oscillating bubbles.

Blogger: Catharina de Lange Davies, professor Department of Physics, NTNU A prerequisite for successful chemotherapy is that the drugs reach its target, and that damage to healthy tissue is limited. However, when drugs are injected into the blood, less than 1% of the drugs accumulate in tumours. Microbubbles combined with…

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Deep research: keeping fit on the bottom of the North Sea

Deep saturation divers

Blogger: Fatima Zohra Kiboub Industrial PhD Candidate, Lead QHSE Engineer, Technip       Crucial to our gas and oil industry, the offshore divers perform their work on the ocean floor of the Norwegian continental shelf. Not unlike the astronauts, these divers – the aquanauts – encounter environments that challenge…

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Ask a researcher: Can dead neurons grow again?


Can dead neurons grow again in stroke patients? And, how far are the research from brain transplantation of the whole or parts of the brain?   Answer from: Ioanna Sandvig, Research scientist at Department of Neuroscience, NTNU and Visiting research scientist, John Van Geest Centre for Brain Repair, University of…

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Improving nanoparticles for battling cancer

Figure 1. A: General design of a nanoparticle loaded with drug. The core/shell/surface coating can be composed of a variety of different materials, which has resulted in an enormous diversity in the design, and hence properties, of different nanoparticles. B: When a drug loaded nanoparticle is injected into the blood, it can leak into the tumour tissue due to the leaky tumour blood vessels. C: General design of a targeted nanoparticle loaded with drug. D: Nanoparticles can be specifically targeted to the cells making up the tumour vasculature. When these are injected into the blood, they accumulate in the tumor vasculature. The targeting and subsequent disrupting of tumour blood vessels is a promising therapeutic strategy. E: Nanoparticles can also be specifically targeted to cancer cells. When these targeted nanoparticles are injected into the blood, they accumulate in the tumor and bind to tumor cells, increasing the amount of drug delivered to individual cancer cells.

Blogger: Sjoerd Hak   The Research Council of Norway has recently awarded grants under the funding scheme Independent Basic Research Projects – Medicine, Health Sciences and Biology (FRIMEDBIO). There is tough competition for this funding nationally, and only the best projects get through. The Faculty of Medicine, NTNU, has been…

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